This book describes patterns of behavior that collectively allow universities toampnbspexchange knowledge more effectively with industry accelerate innovation andampnbspeventually contribute to economic development. These are based on the effectiveampnbsppractices of leading and ambitious universities around the world that the authors haveampnbspbenchmarked and the personal experiences of the authors in a number of internationalampnbspinstitution building projects including those of MIT.The authors provide guidance that is globally applicableampnbspbut must be locally adapted. The approach is first to describe the context in whichampnbspuniversities act as engines of economic development and then present a set of effectiveampnbsppractices in four domains education research innovation and supporting practices.ampnbspEach of these domains has three to six practices and each practice is presented in aampnbspsimilar template with an abstract a rationale and description key actions and one orampnbsptwo minicase studies.ampnbspThe practices are summarized by integrative case studies.ampnbspThe bookFocuses on a globally adaptable set of effective practices complemented by caseampnbspstudies that can enhance universities contribution to economic developmentampnbspbased on an integrated view of education research and innovationPresents effective practices and broader insights that come from real globalampnbspexperience spelled out in templates and explained by casesIncludes tangible resources for university leaders policy makers and fundersampnbspon how to proceed.